• News and Publications

    PRs, Journals, Clinical
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    Comparative preclinical evaluation of AS01 versus other Adjuvant systems in a candidate herpes zoster glycoprotein E subunit vaccine

    In a preclinical model, GSK scientists report a greater immune response to GSK Shingles vaccine (Hz/su) formulations that contain QS-21.

    Hz_su_NEJM_nejmoa150118

    NEJM Reports Efficacy of QS-21 Containing Herpes Zoster Subunit Vaccine

    GSK reports over 97% efficacy for their QS-21 containing Shingles vaccine in a large Phase III trial enrolling a total...

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    Vaccine Adjuvant Systems containing monophosphoryl lipid A andQS-21 induce strong humoral and cellular immune responses against hepatitis B surface antigen which persist for at least 4 years after vaccination

    Vaccine report concluding that QS-21 containing formulations of HBsAg induced high quality and persistent humoral and cellular immune responses that...

    tejada_bioorg

    Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol

    Report detailing the synthesis and preclinical evaluation of QS-21/tucaresol analogs.

    tejada_nchem

    Nature Chemistry: Development of a minimal saponin vaccine adjuvant based on QS-21

    Adjuvance cofounders report the design, develop and adjuvant activity of novel, truncated QS-21 analogs.

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    Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer

    Adjuvance’s co-founding scientists review the application of natural and synthetic QS-21 in cancer vaccinology.

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    KEY PATENT AWARDED TO ADJUVANCE CO-FOUNDERS FOR PIONEERING METHOD OF PRODUCING RARE VACCINE COMPONENT.

    NEW YORK, November 14, 2012 – Adjuvance Technologies, Inc. announced that the United States Patent and Trademark Office has granted Adjuvance...

    chea

    Synthesis and Preclinical Evaluation of QS-21 Variants Leading to Simplified Vaccine Adjuvants and Mechanistic Probes

    Adjuvance cofounders describe the design and preclinical adjuvant activity of novel TiterQuil adjuvants that provide insight into the mechanism of...

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    NEJM: First Report of RTS,S/AS01 Phase 3 results

    The RTS,S Clinical Trials Partnership reports the results of Phase 3 study of the efficacy, safety, and immunogenicity of a...

    Xconomy

    XCONOMY

    Sloan-Kettering Spinoff Adjuvance Gains Traction For Vaccine Tech